Simple Heuristics That Make Us Smart invites readers to embark on a new journey into a land of rationality that differs from the familiar territory of cognitive science and economics. Traditional views of rationality tend to see decision makers as possessing superhuman powers of reason, limitless knowledge, and all of eternity in which to ponder choices. To understand decisions in the real world, we need a different, more psychologically plausible notion of rationality, and this book provides it. It is about (...) fast and frugal heuristics--simple rules for making decisions when time is pressing and deep thought an unaffordable luxury. These heuristics can enable both living organisms and artificial systems to make smart choices, classifications, and predictions by employing bounded rationality. But when and how can such fast and frugal heuristics work? Can judgments based simply on one good reason be as accurate as those based on many reasons? Could less knowledge even lead to systematically better predictions than more knowledge? Simple Heuristics explores these questions, developing computational models of heuristics and testing them through experiments and analyses. It shows how fast and frugal heuristics can produce adaptive decisions in situations as varied as choosing a mate, dividing resources among offspring, predicting high school drop out rates, and playing the stock market. As an interdisciplinary work that is both useful and engaging, this book will appeal to a wide audience. It is ideal for researchers in cognitive psychology, evolutionary psychology, and cognitive science, as well as in economics and artificial intelligence. It will also inspire anyone interested in simply making good decisions. (shrink)

Bradford C Bemiss, Chad A WittDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO, USA: Chronic rejection is a major cause of death after the first year following lung transplantation. Bronchiolitis obliterans is the most common pathologic finding on biopsy, characterized by fibrous granulation tissue, which obliterates the lumen of the bronchiole. Clinically, in the absence of tissue for pathology, BO syndrome refers to a progressive irreversible drop in the forced (...) expiratory volume in 1 second. Recently, a broader definition of chronic rejection, termed "chronic lung allograft dysfunction", has been used to encompass a more inclusive definition of posttransplant dysfunction. Recently, the lung transplant community has come to realize that chronic rejection may be the final common result after repetitive epithelial insults. Acute rejection, infection, and alloreactivity to mismatched HLA antigens are a few of these insults that damage the surface of the bronchioles. Recent evidence of autoimmunity to the normally hidden structural proteins collagen V and K-α1 tubulin have been correlated with a BO phenotype as well, perhaps correlating the epithelial damage with a mechanism for developing BO lesions. Many immunomodulatory medications and treatments have been studied for effectiveness for the treatment of chronic lung allograft dysfunction. New drugs, which more precisely target the immune system, are being developed and tested. Further study is required, but recent advances have improved our understanding of the pathogenesis and potential intervention for this common and deadly complication of lung transplantation.Keywords: lung transplant, bronchiolitis obliterans syndrome, rejection. (shrink)

This book offers an original and detailed reading of Plato's _Republic_, one of the most influential philosophical works in the emergence of Western philosophy. The author discusses the _Republic_ in terms of discursive events and political acts. Plato's act is placed in the context of a politico-discursive crisis in Athens at the end of the fifth and the beginning of the fourth century B.C that gave rise to the dialogue's primary question, that of justice. The originality of Dr. Ophir lies (...) in the way he reconstructs the _Republic's_ different spatial settings - utopian, mythical, dramatic and discursive - using them as the main thread of his interpretation. Against the background of Plato's critique of the organisation of civic-space in the Greek _polis_, the author relates the spatial settings in the Plato text to each other. This provides a basis for a re-examination of the relationship between philosophy and politics, which Plato's work advocates, and which it actually enacted. (shrink)

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be (...) preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

The social, educational and political writings of Jean-Jacques Rousseau have become enormously influential in the 200 years since his death. But the breadth as well as the depth of Rousseau's achievement - he was amongst other things a creative writer and musical composer as well as a philosopher - is not always appreciated. In around 100 articles, alphabetically arranged and fully cross-referenced, N. J. H. Dent explores all facets of Rousseau's work and thoughts, while his subject's remarkable life is summarized (...) in a biographical introduction. Details of works by and about Rousseau are listed in an extensive bibliography. For students or general readers seeking an introduction to Rousseau's work, and for those already familiar with the material who require a convenient reference source, this dictionary is essential reading. (shrink)

A new criterion is introduced for judging the suitability of various fuzzy logics for practical uncertain reasoning in a probabilistic world and the relationship of this criterion to several established criteria, and its consequences for truth functional belief, are investigated.

Chalmers' (2018) meta-problem of consciousness emphasizes unexpected common ground between otherwise incompatible positions. We argue that the materialist should welcome discussion of the meta-problem. We suggest that the core of the metaproblem is the seeming arbitrariness of subjective experience. This has an unexpected resolution when one moves to an interventionist account of scientific explanation: the same interventions that resolve the hard problem should also resolve the meta-problem.

Over the past few decades, there has been increasing attention focused on the ethics of health research, particularly in low- and middle-income countries. Despite the increasing focus on the literature addressing human protection, community engagement, appropriate consent procedures and ways to mitigate concerns around exploitation, there has been little discussion about how the duration of the research engagement may affect the ethical design and implementation of studies. In other words, what are the unique ethical challenges when researchers engage with host (...) communities for longer periods (10 years or more), and what special considerations does this time commitment generate when applying ethical principles to these kinds of studies? This article begins to outline key areas of ethical concern that arise during long-term, sustained research activities with communities in low-resource settings. Through a review of the literature and consultations with experts in health systems, we identified the following key themes: fair benefits and long-term beneficence; community autonomy, consultation and consent; impacts on local health systems; economic impacts of research participation; ethical review processes; and institutional processes and oversight within research organizations. We hope that this preliminary exploration will stimulate further dialogue and help inform ethical guidance around long-term research engagements in the developing world. (shrink)

Aristotle, great Greek philosopher, researcher, reasoner, and writer, born at Stagirus in 384 BCE, was the son of Nicomachus, a physician, and Phaestis. He studied under Plato at Athens and taught there ; subsequently he spent three years at the court of a former pupil, Hermeias, in Asia Minor and at this time married Pythias, one of Hermeias's relations. After some time at Mitylene, in 343?2 he was appointed by King Philip of Macedon to be tutor of his teen-aged son (...) Alexander. After Philip's death in 336, Aristotle became head of his own school, the Lyceum at Athens. Because of anti-Macedonian feeling there after Alexander's death in 323, he withdrew to Chalcis in Euboea, where he died in 322. Nearly all the works Aristotle prepared for publication are lost; the priceless ones extant are lecture-materials, notes, and memoranda. They can be categorized as follows: I Practical: Nicomachean Ethics; Great Ethics ; Eudemian Ethics; Politics; Economics ; On Virtues and Vices. II Logical: Categories; Analytics ; Interpretation; Refutations used by Sophists; Topica. III Physical: Twenty-six works including astronomy, generation and destruction, the senses, memory, sleep, dreams, life, facts about animals, etc. IV Metaphysics: on being as being. V Art: Rhetoric and Poetics. VI Other works including the Constitution of Athens; more works also of doubtful authorship. VII Fragments of various works such as dialogues on philosophy and literature; and of treatises on rhetoric, politics and metaphysics. The Loeb Classical Library edition of Aristotle is in twenty-three volumes. (shrink)

The systems approach to niche presented herein stands as an example of the unifying potential of mathematical system theory when applied to concepts and principles of ecology. Beginning with subjective concepts from the naturalistic tradition, the niche was framed in the formalism of general system theory. So modeled, it appeared as a restriction of a more general construct, the environ. Both niches and environs are implementable in the context of ecosystem models, and with the growing ability of ecologists to construct (...) such models, system theoretic niches and environs both should serve in the future to clarify old problems of ecology, and make it possible to raise new classes of problems. The nature of niches, always difficult conceptually for the ecologist, may now give way to further development, both theoretical and empirical. (shrink)

This out of print work offered researchers a comprehensive and easy to use bibliography of primary and secondary works by or about Collingwood. More than 1,200 citations were listed alphabetically by standard bibliographical categories in this volume, which contained a periodical index as well as author and subject indexes. In addition, each book entry included a "review alert" listing the names of reviewers. Author notes clarified the significance of a listed work when this was not apparent from the title, and (...) the number of pages was indicated for very long or very short monographs. This volume remains a standard reference work for Collingwood scholars and it is available in research libraries around the country. (shrink)

It is often taken for granted that there is a crucial dichotomy between positive science, with its interest in what is the case, and morality, with its supposed interest in what ought to be the case. This assumption takes its departure from a belief in the notion of unconditional or categorical obligation or ?the moral? as ?that whose nature it is to be required or demanded?. The notion of unconditional or categorical obligation, together with the assumption that there is a (...) dichotomy between considerations of what is the case and what ought to be the case, however widespread and entrenched this notion and assumption might be, are logically confused. But to demonstrate this logical confusion is not the only task confronting ethical theory. Another, and often neglected task, is to draw attention to the ethical origins of this confusion in a particular way of life. Hegel's distinction between Moralität (Moral Life) and Sittlichkeit (Ethical Life) is of critical importance here. The obstacle to the development of ethical theory, then, is not some abstract ?logical confusion?, but is, rather, the way of life (Moral Life) of which this confusion is a natural expression. (shrink)

The paper is an attempt to make sense of Hegel's notion of aufheben. The double meaning of aufheben and its alleged ?rise above the mere ?either?or?; of understanding? have been taken, by some, to constitute a criticism of the logic of either?or. It is argued, on the contrary, that Hegel's notion of aufheben, explicated in its primary and philosophical context, turns out to be a substantiation of that logic. The intelligibility of the formula of either?or depends, for example, on the (...) categories of Being and Not?Being. But if these categories are regarded as particular finite determinations themselves subject to the formula of either?or, then the formula, far from being intelligible, ?falls apart?. Hegel is arguing, in other words, that if we are to substantiate the logic of either?or, we must, at the same time, ?rise above? that logic. The role of aufheben is then considered in the special sciences. Here it is argued that we must distinguish between empirical transitions, governed by the finite determinations of things, and logical or dialectical transitions, governed by considerations of the intelligibility of the notions involved. Applying the notion of aufheben to the former transitions suggests wrongly that empirical transitions have an objective or philosophic necessity. Finally, the place of ?immanent transformation? in the context of aufheben is examined. It is concluded that if there is to be a transformation, then a distinction must be drawn between thought and its content, but then the transformation cannot be regarded as immanent. (shrink)